Sepragen's Sepraflo Resins are designed for process scale separation of biological molecules. They can be run at very high flow rates, typically up to 50% higher than commonly used resins from other suppliers. They have large nominal 300A pore size that facilitates rapid mass transfer of large macromolecules and provides for high static and dynamic binding capacity. They are cleanable with 1N sodium hydroxide.
Sepraflo resins consist of macroporous beads with nominal 50 micron size. They are rigid and can withstand pressures in excess of 500 psi. They can be supplied by Sepragen in batches of 100 liters on up. The resins are made of a hydrophilic copolymer of glycidyl methacrylate which is used predominantly in making contact lenses. The Sepraflo resins are priced at a fraction of the price of competitive resins.
The resins are available in both a strong cation exchange or sulpho propyl chemistry and a strong anion exchange quaternary amino ethyl chemistry.