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Brand: Sepragen
Category: Chromatography Consumables & Accessories
Industry: Life Science and Biotechnology, Pharma, Bio-pharma & Vaccine, Clinical Research & Diagnostics
The QuantaSep® 5000 is a mobile, compact, and fully integrated chromatography system engineered for mid-scale purification and process development.
Designed to deliver exceptional control, reliability, and scalability, it offers a dynamic flow range from 50 mL/min to 5 L/min, making it an ideal bridge between benchtop R&D systems and full-scale production units.
Equipped with dual positive displacement pumps, intelligent buffer management, in-line sensors, and a fraction collection suite, the QuantaSep® 5000 empowers process engineers and scientists to execute chromatography methods with unmatched precision, reproducibility, and traceability.
The QuantaSep® 5000 redefines efficiency in mid-scale chromatography automation.
It integrates every essential function for gradient formation, buffer switching, sample loading, air ejection, and fraction collection — all within a mobile and space-efficient design.
With its intuitive software platform, users can control processes via conductivity, pH, time, pressure, or sensor feedback, enabling automated responses to real-time conditions.
The system automatically logs and archives every process event, including alarms for overpressure, air detection, and leakage, ensuring complete data integrity and process validation.
Whether used for pilot plant operations, vaccine purification, or clinical-scale production, the QuantaSep® 5000 offers industrial-grade reliability in a compact footprint — the perfect balance between flexibility and power.
Integrated Multi-Step Chromatography Automation
Executes buffer switching, gradient formation, and fraction collection seamlessly.
Real-Time Sensor Feedback
pH and conductivity monitoring before and after the column ensures process consistency and reliability.
Powerful Process Logic Control
Automatically triggers buffer or fraction changes based on predefined process thresholds.
Digital Data Archiving
Logs all events, conditions, and alarms to support compliance, traceability, and reproducibility.
Bidirectional Flow Architecture
Allows both forward and reverse flow for flexible purification strategies and column cleaning.
Dynamic Flow Range: 50 mL/min to 5 L/min — ideal for pilot and small production runs
Dual Positive Displacement Pumps: Delivers consistent, pulsation-free flow
Advanced Buffer Management: 8 buffer selection valves for seamless switching
In-Line Mixing and Filtration: Integrated inline mixer and pre-column filters ensure homogeneity and purity
Multi-Parameter Monitoring: Real-time pH and conductivity sensing (pre- and post-column)
Automated Fraction Collection: 6 fraction collection valves for precision output
Forward and Reverse Flow Control: Enables versatile operation modes for complex separations
Alarm and Event Logging: Automatic detection and archival of overpressure, leaks, and air ingress events
Compact, Mobile Configuration: Lightweight, portable chassis for easy relocation in GMP and pilot lab environments
User-Friendly Software Interface: Intuitive control over gradients, alarms, and process conditions
Smart Chromatography, Anywhere You Need It.
The QuantaSep® 5000 combines mobility, automation, and precision to deliver reliable, data-driven purification in compact form.
With a 50 mL–5 L/min flow range, dual pump control, and intelligent sensor feedback, it’s the perfect choice for biopharma teams scaling up from R&D to pilot and production environments — with confidence and control.
| Parameter | Specification |
|---|---|
| Flow Rate Range | 50 mL/min – 5 L/min |
| Pump Type | Dual positive displacement pumps |
| Buffer Management | 8 buffer selection valves with inline mixer |
| Fraction Collection | 6 fraction valves with programmable switching |
| Sensor Integration | pH and conductivity sensors (pre- and post-column) |
| Flow Direction | Forward and reverse flow |
| Process Control | Time, volume, conductivity, pH, and pressure feedback |
| Software Platform | Windows®-based intuitive control interface |
| Event Logging | Automated event, alarm, and process archival |
| System Mobility | Compact, wheeled design for easy movement |
Monoclonal Antibody Purification
Reliable performance for therapeutic and biosimilar downstream processing.
Vaccine and Viral Vector Production
Accurate gradient control and scalable purification for vaccine intermediates.
Protein and Enzyme Purification
Efficient and reproducible recovery of biomolecules across a range of molecular weights.
Process Development and Optimization
Ideal for method scale-up from R&D to pilot and production stages.
GMP and Pilot-Scale Operations
Compact and compliant design suitable for regulated environments.
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