Name: Process Scale Columns
Brand: Sepragen
SKU: FKOKHNFC
Availability: InStock

Process Scale Columns

FKOKHNFC

Brand: Sepragen

Category: Chromatography Consumables & Accessories

Industry: Life Science and Biotechnology, Pharma, Bio-pharma & Vaccine, Clinical Research & Diagnostics

The Superflo® Process-Scale Radial Columns are purpose-built for large-scale bioprocess separations and GMP manufacturing environments, combining robust engineering with superior flow dynamics.

Available in 10L to 200L sizes, these columns deliver consistent, high-efficiency separations with an effective bed depth of 10 cm, making them ideal for industrial purification processes that demand scalability, reliability, and ease of operation.

Constructed in biocompatible acrylic or solvent-compatible stainless steel, Superflo® columns provide flexibility across a broad range of biomolecular and pharmaceutical applications. Larger capacities are available upon request for extended production requirements.

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The Superflo® Process-Scale Radial Flow Columns are designed to meet the rigorous demands of GMP-scale downstream processing, offering exceptional uniformity, flow distribution, and scalability.
Their radial flow geometry minimizes pressure drop and enhances mass transfer efficiency, ensuring high productivity and consistent performance even at large volumes.

Each column is constructed with precision-engineered components that ensure sanitary operation, easy cleaning and assembly, and long-term durability in regulated production environments.
With options for both acrylic and stainless-steel construction, Superflo® columns adapt seamlessly to diverse applications — from protein purification and monoclonal antibody capture to vaccine and enzyme production.

These columns integrate effortlessly with process chromatography systems such as the QuantaSep® Series, supporting both batch and continuous processing workflows.
For facilities requiring expanded throughput, custom configurations beyond 200L can be designed to meet specific process needs.

Core Technologies

Radial Flow Engineering
Optimized flow path ensures uniform velocity and minimal channeling, delivering reproducible separations at scale.
GMP-Compliant Design
Built for cleanability, durability, and regulatory validation, suitable for FDA and EMA-regulated facilities.
Versatile Material Selection
Choose between acrylic for visual inspection and stainless steel for solvent-intensive operations.
Scalable Performance
Maintains consistent performance across a wide range of bed volumes — from 10L pilot scale to 200L full production.
Custom Engineering
Columns exceeding 200L capacity can be tailored for continuous or hybrid chromatography workflows.

Volume Range: Available in 10L to 200L, with larger sizes on request
Effective Bed Depth: Standardized 10 cm for consistent chromatographic performance
Material Options:
- Acrylic: Biocompatible for aqueous and protein-based applications
- Stainless Steel: Solvent-compatible and robust for industrial use
Radial Flow Design: Provides uniform flow distribution, low pressure drop, and high separation efficiency
GMP-Ready Construction: Sanitary design for compliance and ease of validation
Modular Assembly: Facilitates quick setup, cleaning, and maintenance
Scalable Integration: Compatible with QuantaSep® process systems and other large-scale chromatography setups
Custom Sizes: Columns above 200L available for large-batch or continuous processes

Scale Up with Confidence. Perform with Precision.
The Superflo® Process-Scale Radial Columns (10L–200L) deliver unmatched flow uniformity, structural integrity, and scalability for industrial purification workflows.
Whether in acrylic for biocompatibility or stainless steel for solvent resilience, Superflo® columns ensure reliable, reproducible, and GMP-compliant performance — empowering large-scale bioprocessing with confidence and control.

Parameter	Specification
Column Volume Range	10L – 200L (custom sizes available)
Effective Bed Depth	10 cm
Material Options	Biocompatible acrylic or solvent-compatible stainless steel
Design Type	Radial flow geometry
Operating Mode	Batch or continuous chromatography
Applications	Protein, mAb, enzyme, and vaccine purification
GMP Compliance	Sanitary, validated design for production use
Customization	Larger capacities available upon request

Monoclonal Antibody Purification
High-efficiency, low-pressure separation for large-batch antibody capture and polishing.
Vaccine and Viral Vector Processing
Scalable column architecture for purification of vaccine intermediates and viral particles.
Protein and Enzyme Purification
Reliable separations with excellent flow uniformity and low shear for sensitive biomolecules.
GMP Manufacturing
Designed for validated processes requiring reproducibility, traceability, and operational control.
Continuous and Batch Bioprocessing
Supports both production modes with consistent flow and separation efficiency.

Process Scale Columns