TVJHGT2Y
Brand: Tescan
Category: Microscope - Scanning Electron
Industry: Life Science and Biotechnology, Pharma, Bio-pharma & Vaccine, Clinical Research & Diagnostics
The TESCAN CRYO FIB-SEM is an integrated cryogenic sample preparation and imaging platform designed for precise, contamination-free TEM lamella fabrication from plunge-frozen biological specimens.
It combines superior low-kV SEM imaging, optimized cryo-TEM workflows, and flexible cryo-stage control to deliver artifact-free, on-grid lamellae — enabling seamless transition from vitrified sample to high-resolution TEM imaging.
With intuitive navigation, advanced collision modeling, and a dedicated cryo-user interface, the system ensures safe, reproducible, and high-quality cryo-FIB milling for even the most demanding life science applications.
The TESCAN CRYO FIB-SEM redefines the standards for cryo-electron microscopy sample preparation, offering researchers a fully integrated environment for working under true cryogenic conditions.
Built for precision, stability, and usability, this flexible workstation enables the creation of planar on-grid cryo-TEM lamellae directly from plunge-frozen samples, preserving native biological structures without ice contamination or beam-induced damage.
Its optimized cryo-FIB-SEM workflow ensures exceptional reproducibility and throughput — from coarse milling to final thinning — while maintaining structural integrity across all stages of sample handling.
The system supports compatibility with all major cryo-TEM systems, providing a seamless bridge between preparation and imaging. Advanced features like extended field-of-view navigation, dual-camera visualization, and a 3D active collision model simplify operation, making it ideal for both expert users and new entrants in cryo-EM research.
With a dedicated cryo-user account, DrawBeam™ project integration, and customizable modular software, users can tailor every workflow parameter to their research — whether in cell biology, molecular medicine, or drug discovery.
Flexible Cryo-FIB-SEM Workstation — Perform demanding cryo applications with maximum control and stability.
Optimized Cryo-TEM Lamella Workflow — Prepare artefact-free, planar on-grid lamellae from vitrified biological samples.
Universal Compatibility — Fully compatible with all major cryo-TEM systems available on the market.
Excellent SEM Imaging at Low kV — Achieve high-contrast imaging with minimal beam damage.
Dedicated Cryo-User Account — Includes DrawBeam™ project environment designed for cryo operations.
Easy Navigation & Visualization — Extended field-of-view, dual-camera setup, and 3D active collision modeling.
Application-Oriented Interface — Fully customizable modular GUI for efficient and reproducible cryo workflows.
Optional Application Packages — Enhance capability with specialized modules tailored to various life science research needs.
Preserve Nature. Perfect Precision.
The TESCAN CRYO FIB-SEM enables researchers to push the frontiers of cryo-electron microscopy with unmatched precision and reproducibility.
From vitrified cell samples to complex biological assemblies, it ensures artifact-free lamella preparation, low-dose imaging, and streamlined navigation — all under true cryogenic conditions.
Built for the most demanding life science environments, this workstation turns the challenge of cryo sample preparation into a confident, automated, and efficient process — ready for the next breakthrough in structural biology and molecular medicine.
| Parameter | Specification |
|---|---|
| Operating Mode | Cryogenic dual-beam FIB-SEM |
| Sample Environment | Sub-zero (vitrified) cryogenic condition |
| Lamella Preparation Workflow | Optimized for plunge-frozen biological samples |
| Imaging Performance | Excellent SEM contrast at very low accelerating voltages |
| Cryo Control System | Integrated temperature regulation and anti-contamination |
| User Interface | Dedicated cryo-user account with DrawBeam™ integration |
| Navigation System | Dual cameras with 3D collision modeling and wide field view |
| Compatibility | All commercial cryo-TEM systems |
Cryo-TEM Lamella Preparation — Produce thin, high-quality lamellae for cryo-electron tomography and single-particle analysis.
Cellular Structure Studies — Visualize intracellular components under native, vitrified conditions.
Structural Biology — Investigate macromolecular complexes and protein assemblies in their natural state.
Biomedical Research — Study disease mechanisms at the molecular level with high preservation fidelity.
Pharmaceutical Development — Analyze drug interactions and nanoscale formulations under cryogenic conditions.
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