Live Cell Imaging - World Precision Instruments

Traditional microscopy relied on fixed or stained cells. Today, thanks to miniaturized incubators and environmental control technology, researchers can maintain living cells under optimal conditions directly on the microscope stage — enabling continuous observation and time-lapse studies without compromising cell health.

WPI’s Live Cell Imaging (LCI) product line includes stagetop environments, microscope enclosures, and environmental control units (ECUs) that regulate temperature, CO₂, O₂, humidity, and airflow.

From short-term imaging to long-term culture observation, WPI provides complete, modular systems for live-cell monitoring, fluorescence microscopy, and drug-response analysis — helping scientists visualize life in motion.

LCI Accessories

Environmental Control Units and System Enhancements

WPI offers a variety of Environmental Control Units (ECUs) and accessories that maintain precise environmental stability within live-cell imaging chambers.

These accessories ensure uniform temperature control, gas composition management, and optimized humidity, critical for sustaining healthy cells during prolonged imaging sessions.

Key Features:

• Integrated temperature, CO₂, and O₂ regulation

• Rapid-response humidity control

• Compact and quiet operation

• Compatible with all WPI stagetop and enclosure systems

Applications:

Long-term live-cell culture imaging, fluorescence microscopy, and pharmacological screening.

Microscope Enclosures

Comprehensive Environmental Control for the Entire Microscope System

For experiments requiring maximum environmental stability, WPI’s custom-designed acrylic enclosures provide a fully controlled atmosphere around the entire microscope.

Each enclosure integrates seamlessly with the ECU, offering the same environmental regulation available in the stagetop systems — across a larger internal volume.

Configuration Options:

1. Temperature Only

2. Temperature + CO₂

3. Temperature + CO₂ + O₂

Highlights:

• Transparent acrylic construction for easy viewing

• Complete microscope coverage to prevent heat or gas loss

• Compatible with all major inverted and upright microscope models

Applications:

High-sensitivity imaging, fluorescence time-lapse studies, and long-term live-cell monitoring.

Stagetop Systems

Compact Incubation Chambers for On-Stage Cell Culture Imaging

WPI’s Stagetop Environment (STEV) systems fit securely on any inverted microscope stage, allowing researchers to observe living cell cultures directly in standard multi-well plates.

When paired with the Environmental Control Unit, these compact incubators maintain a stable, physiological environment — regulating temperature, humidity, CO₂, and O₂ levels precisely where cells are imaged.

Highlights:

• Universal fit for most inverted microscope stages

• Accommodates multiple culture well plates

• Ideal for time-lapse video studies and dynamic cell tracking

• Minimal footprint, maximum environmental stability

Applications:

Live-cell imaging, embryology, developmental biology, and cellular dynamics research.

Stagetop vs. Microscope Enclosure Systems